Kevin Bryant Board Director | Children's Mercy Hospital K.C.
Kevin Bryant Board Director | Children's Mercy Hospital K.C.
Researchers at Children's Mercy Kansas City's Genomic Medicine Center have developed a cost-effective and rapid method to create organoids, which are three-dimensional cell models that replicate an individual's organs. Traditional methods of growing organoids from patient-derived induced pluripotent stem cells can take up to a year and cost around $10,000. The new approach reduces this to approximately $200 and takes only two to three weeks.
Scott Younger, the director of disease gene engineering at the center, discussed this advancement in detail. He explained how the team tested their method by matching three children with Duchenne muscular dystrophy to an antisense oligonucleotide therapy. This breakthrough could significantly impact the development of customized therapies for individuals with rare genetic diseases.
The findings were published in Nature, highlighting the potential transformative effect on personalized medicine research.
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